Search results for "Dialysate sodium"

Model-Based Decision Support System for Individual Prescription of the Dialysate Bicarbonate Concentration in Hemodialysis

1992

A decision support system has been developed that determines the optimal dialysate bicarbonate concentration in hemodialysis therapy for each patient individually. The knowledge about the behavior of the acid-base state during treatment has been provided by a mathematical model for the description of dynamic exchange processes during hemodialysis. This model simulates the sodium and water distribution, the acid-base state as well as the ventilation. The decision support system uses the model for the prediction of the end-dialysis acid-base state and calculates by means of linear optimization the dialysate bicarbonate concentration which is necessary to reach a specified end-dialysis state.…